Nanoscale Properties of Biocompatible materials

Publicado: 22 Nov 2017Vistas 30 días: 23Vistas totales: [totalcount]
Tema(s):
Resumen:
1 INRS Energy, Materials and Telecommunications, Varennes (Canada)
 
Modifying the nanostructure/chemistry of materials allows to optimize their properties [1]. Our strategy rests on creating nanopatterns that act as surface cues [2,3], affecting cell behavior. Chemical oxidation creates unique topographies [4], becoming a general strategy to improve biocompatibility. Our treatment selectively inhibits fibroblast growth while promoting osteogenic cell activity [5] in vitro. Enhancement of mechano-biocompatibility may occur by coating with spider silk [6, 7]. Improvement of antibacterial properties using laser and plasma strategies will also be discussed [8-11].
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[3]F Variola et al, Biomaterials 29, 1285 (2008)
[4]F Vetrone et al, Nanolett 9, 659 (2009)
[5]L Richert et al, Adv Mater 20, 1488 (2008)
[6]C Brown et al, Nanoscale 3, 3805 (2011)
[7]C Brown et al, ACS Nano 6, 1961 (2012)
[8]O Seddiki et al, Appl Surf Sci 308, 275 (2014)
[9] M Cloutier et al, Diam Rel Mater 48, 65 (2014)
[10] L Cardenas et al, Nanoscale 6, 8664 (2014)
[11] M. Cloutier et al., Trends Biotechnol. 33, 637 (2015).
 



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